Steriflow Valve offers sanitary check valves designed specifically for pharmaceutical, biopharmaceutical, and other high-purity applications. Selecting the right Steriflow check valve requires considering line size, flow rate, installation orientation, cracking pressure, process media, temperature, and material compatibility.
Start with the line size and expected flow range. Cracking pressure — the differential pressure required to open the check valve — should also be appropriate for the application. A cracking pressure that is too high can restrict flow and create unnecessary pressure drop, while improper selection can contribute to unstable operation or chattering.
Steriflow offers sanitary check valves for several piping orientations and applications:
• SVC Series Downflow check valves are designed for vertical liquid drain lines. They remain open to allow drainage and close when water-based process fluid backs up and rises in the drain line.
• SVC Series Upflow check valves are designed for vertical piping with upward flow.
• SHC Series check valves are designed for horizontal piping installations.
Steriflow sanitary check valves feature springless, crevice-free designs that eliminate the springs and associated entrapment areas found in traditional spring-loaded sanitary check valves. This helps reduce potential particulate generation and supports cleanability in aseptic and high-purity processes.
For material selection, 316L stainless steel is appropriate for most sanitary and high-purity applications. Hastelloy C-22 is available for applications involving more aggressive process or buffer chemistries where additional corrosion resistance is required. Product-contact seal and seat materials should also be selected for chemical and temperature compatibility and meet applicable FDA and USP Class VI requirements.
Steriflow sanitary check valves are designed in accordance with applicable ASME BPE valve design guidelines and are compatible with CIP, SIP, and autoclave processes.
For final selection, consider line size, flow requirements, installation orientation, cracking pressure, process media, temperature, cleaning and sterilization requirements, and material compatibility.